- Peds: see below
- Alternative: 500 mg daily x3 days
- Alternative (extended-release suspension): 2 gm single dose
- Chlamydia (STD): Extended-release suspension 1 gm single dose
- Alternative: 10 mg/kg daily x3 days
- Alternative: 30 mg/kg as single dose (max. 1500 mg)
- Peds: 50 mg/kg IM
- Peds: 50 mg/kg IM
- Peds: 20-30 mg/kg/d in 2 divided doses
- Peds: 25-50 mg/kg/d in 4 divided doses
- Peds: 15 mg/kg/d in 2 divided doses
- Peds: 10-40 mg/kg/d divided in q8h doses
- Peds: 25-50 mg/kg/d in 4 divided doses
- Peds >8 y.o.: 2 mg/kg/dose B.I.D.
- Peds: Avoid
- 10-20 mg/kg/d for Pen-allergic without other options
- Peds: See below
* I’ve seen a variety of oral TMP-SMX doses used for MRSA. The Infectious Disease Society of America Guidelines hedge: DS Tablets: 1-2 B.I.D. for 5-10 days. Don’t worry about an overdose: for Pneumocystis pneumonia (PCP) in AIDS, the dose is 2 tabs Q.I.D.
Peds: complicated descriptions
Amoxicillin-clavulanate (doses in terms of amoxicillin component):
> Preparations:- “Standard”: 125 mg or 250 mg / 5 cc
- “Newer”: 200 mg or 400 mg/5cc suspensions; 200 mg or 400 mg chewable tabs
- “Newer” more expensive, not always covered by insurance
- “Standard”: 20-40 mg amoxicillin/kg/day in q8h dosing
- “Newer”: 25-45 mg amoxicillin/kg/day in q12h dosing
Trimethoprim-Sulfamethoxazole (doses in terms of TMP component)
> Preparations:- “Double-Strength” (DS) tab = TMP 160 mg + SMX 800 mg
- “Single-Strength” tab = TMP 80 mg + SMX 400 mg
- Suspension = TMP 40 mg + SMX 200 mg per 5 ml.
> Dosing: 8-12 mg trimethoprim/kg/day in 2 divided doses
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