B19 Parvovirus

Classic symptoms:
  • Slapped-cheek rash (children 60%)
  • Non-specific rashes (adults 75%)
  • Arthralgias very common (esp. adult women)
Immunocompromised:
  • Aplastic Anemia (life-threatening) !!!!!
  • May not get arthralgias or rash
Diagnosis:
  • Immunocompetent: IgM antibody
  • Immunocompromised:  PCR
Diagnosis not important in Immunocompetent Host
  • UNLESS close contact w/ immunocompromised