Celiac Disease

Malabsorption triggered by gluten from wheat, barley, rye, maybe oats

• Prevalence ~1:300 / 1:500
• Occurs in many ethnicities (not just white Europeans)

Test any patient with Chronic Diarrhea or unexplained Iron Deficiency:

• anti-Tissue Transglutaminase IgA Antibody
• anti-Endomysial IgA Antibody
• If negative, rule out IgA deficiency, or test IgG antibodies
• Small bowel biopsy if serology positive
• Tests must be done on gluten-rich diet

See posting Chronic Diarrhea.

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