- Early satiety and weight loss are key clues
- Prognosis poor (prognosis invariably poor anyway).
- Positive Family History Gastric CA
- Immigrant from high-prevalence country (Japan, Chile, Venezuela)
Patients who require ongoing PPI therapy for “dyspepsia” warrant endoscopy to R/O Gastric CA.
- Not pts. w/ GERD.
- Not pts. taking H2-Blockers (famotidine, etc)