Vasculitis (presenting with Arthralgias)

Many kinds:   Large-,  Medium-,  and Small-Vessel
  • All potentially serious
  • All very-to-extremely rare  (H-S Purpura common in pediatrics)

In pt. with non-specific arthralgias, suspect a Vasculitis [in italics] if:

  • Mononeuritis Multiplex: asymmetric polyneuropathy  [Polyarteritis Nodosa]
  • Purpura, Petichiae  [Henoch-Schonlein, Polyarteritis Nodosa, Hypersensitivity Vasculitis, Cryoglobulinemia]
  • Epistaxis, Nasal Ulcers [Polychondritis, Granulomatosis]
  • Hematuria w/ casts / proteinuria [Microscopic Polyarteritis]
  • “Subclavian Steal”:  Dizzy / faint / other CNS Sx which occur with arm exercise [Takayasu’s]