Alcoholism (as cause of high MCV)

Regular intake of ~5 drinks/day (750 cc wine) → ↑ MCV
  • MCV usually <110
  • Mechanism unknown
  • Often no frank anemia
  • Normalizes after ~2 mos. of abstention

Suspect Closet Alcoholism in patients with ↑ MCV of unknown etiology.

See posting Anemia – 3.