Anemia of Chronic Disease (ACD)

Mild Anemia, rarely below Hb 10 gm / Hct 30%
  • Usually Normocytic (MCV 80-100)
  • If microcytic, MCV 75-80

Decreased bone marrow production; many causes:

  • acute inflammation or infection
  • medication effect
  • old age
  • etc. etc.
  • renal / liver failure
  • malignancy
  • collagen-vascular disease
  • etc. etc.

Key Test:  Reticulocyte Count ≤1%

Usually don’t order extensive W/U for cause:
  • Consider ESR
  • Consider Rheum referral if ESR ≥100 mm.

See posting Anemia – 3.